Experimental Neuroscience
gabriella.nicolini@unimib.it
Associate Professor (GSD BIOS-13/A ex SSD BIO-17)
School of Medicine and Surgery, University of Milano-Bicocca
Workplace: Edificio U8, Via Cadore 48, Monza
ORCID ID: 0000-0002-6241-4538
February 1996 Degree in Biological Sciences, University of Milan
2000 Visiting Student c/o Department of Neurology, Cellular Neurobiology Laboratory, Mayo Clinic, Rochester (MN), USA
January 2001 PhD in Morphology Sciences, University of Milan
2001-2005 Post doc fellowship c/o Department of Neuroscience and Biomedical Technology, University of Milano-Bicocca
2005-2007 Research fellowship c/o Department of Neuroscience and Biomedical Technology, University of Milano-Bicocca
2007-2024 Assistant professor (Histology and Embriology) c/o School of Medicine and Surgery (former Department of Neuroscience and Biomedical Technology), University of Milano-Bicocca
2024 to present Associate professor (Histology and Embriology) c/o School of Medicine and Surgery, University of Milano-Bicocca
RESEARCH ACTIVITIES
- Peripheral neurotoxicity induced by antineoplastic drugs (CIPN): in vivo and in vitro models.
Antineoplastic drug targeting studies and in vitro and in vivo studies of neuroprotective agents.
SARM1/NMNAT2 pathway involvement in CIPN. - Glioblastoma molecular and morphological characterization and development of new molecules against glioblastoma. 2D and 3D in vitro models.
ONGOING AND RECENT RESEARCH PROJECTS
– ESRF, European Synchrotron Radiation Facility (ESRF), Grenoble. Multiscale tomographic characterization of 3D bioprinted glioblastoma multiforme for drug screening
– Università degli Studi di Camerino. Progetto: New copper based chemotherapic molecules for the treatment of glioblastoma
– Università degli Studi di Parma. New ALKBH2 and ALKBH5 inhibitors for treating glioblastoma
– SPILLOproject. Biological validation of the software “SPILLO potential binding sites searcher” as a tool to identify targets and off targets of drugs and small molecules.
- 2023-2025 Funding: Filippo Serpero Pharmacological Institute Foundation.
Project “Histone deacetylase 6 (HDAC6) inhibitors: possible neuroprotectors for chemotherapy-induced peripheral neuropathy”
Role: Principal Investigator
- 2022-2024. Funding:Giovanni Celeghin Onlus Foundation against brain tumors.
Project “Multidisciplinary Approach to Optimize The Promising Anti Glioblastoma Candidate MV1035”. Role: Principal Investigator
FURTHER DETAILS
please visit www.linkedin.com/in/gabriella-nicolini-5125b917